During the last 20 years, Central America has seen a dramatic increase of chronic kidney disease, unexplained by conventional risk factors, which primarily affects male labourers in the agricultural sector. Similar increases are also reported from Sri Lanka, India and a few other countries with a subtropical or tropical climate.

In search of understanding this enigmatic disease and identify etiology and preventive measures the First International transdisciplinary Research Workshop on the Mesoamerican Nephropathy (MeN) was held in Costa Rica, November 2012, organized by Programa Salud y Trabajo en América Central (SALTRA). A scientific consortium, CENCAM, was initiated at the 2012 workshop, with the mission to contribute to knowledge generation and to promote and facilitate activities to reduce the occurrence of Chronic Kidney Disease of unconventional (and hitherto unknown) origin in Central America and Mexico. In 2016, CENCAM had 102 members from 21 countries.

The Second International Workshop on MeN was held Nov 18-20, 2015 and the Third International Workshop was held March 20-22, 2019, both in San José, Costa Rica.

Extensive Technical Reports from the three workshops, including state-of-the-art summaries, are available on this site. A continuously updated list of relevant scientific publications on CKDu Chronic Kidney Disease of hitherto unknown origin is also available.